REGEN-COV Monoclonal Antibody Treatment

What is the REGEN-COV Monoclonal Antibody?

REGEN-COV (Casirivimab/Imdevimab) is a monocolonal antibody treatment for COVID-19. Monoclonal antibodies aren't a new technology. They are laboratory-engineered molecules designed to neutralize the spike protein of COVID-19.


Who can get REGEN-COV Monoclonal Antibody?

The FDA has issued an Emergency Use Authorization to permit the use of REGEN-COV (Casirivimab/Imdevimab) for the treatment of mild to moderate COVID-19 in persons who meet ALL of the following conditions:

  1. Adults and pediatric patients (>12 years of age weighing >88 lbs)
  2. Positive COVID testing result
  3. Receive treatment within 10 days of symptom onset
  4. At high risk for progression to severe COVID-19 infection, including hospitalization or death


What qualifies as "high risk for progression to severe COVID-19 infection"?

High-risk groups include:

  • >65 years of age
  • Overweight (BMI >25)
    • If age 12-17, BMI >85th% of their age and gender based on CDC4
  • Pregnancy
  • Chronic kidney disease
  • Diabetes (Type 1 and Type 2)
  • Immunosuppressive disease
  • Currently receiving immunosuppressive treatment
  • Cardiovascular disease/hypertension (high blood pressure)
  • Chronic lung disease
  • Sickle cell disease
  • Neurodevelopmental disorders
  • Medical-related technological dependence (for example, tracheostomy, gastrostomy, or CPAP [not related to COVID-19])


How do I get the REGEN-COV Monoclonal Antibody treatment?

Under the PREP Act, there are several ways you can become eligible for the REGEN-COV Monoclonal Antibody treatment:

  1. Your healthcare provider can issue an order for you to receive treatment.
  • If your healthcare provider does not have our REGEN-COV order form, they can request the form by calling our store at 256-445-5400 or emailing 
  • Bring your positive test result within 10 days of the start of your symptoms and one of our trained pharmacists will determine your eligibility. 
  • Get tested at our store. If you test positive, one of our trained pharmacists will determine your eligibility. 

    For more information on getting tested for COVID-19 infection, click here.




    • How is REGEN-COV administered?  The treatment is given as four injections under the skin. We do not give infusions.
    • If my loved one is going to be admitted to the hospital, can they get the monoclonal antibody treatment?  No. REGEN-COV only has an emergency use authorization for treatment of mild to moderate COVID-19 infection. If someone requires hospitalization, they have progressed to severe infection.
    • I have had the COVID-19 vaccine. Can I still receive the monoclonal antibody treatment?  Yes. Vaccination status is not considered when qualifying a patient for treatment.